Hemostatic Therapy for Intracerebral Hemorrhage

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Hemostatic Therapy for Intracerebral Hemorrhage

Objective: To reduce the blood pressure and elevate intracranial pressure using nimodipine (Nimotop Intravenous (IV) infusion). Thus, intracerebral hemorrhage was controlled, and the purpose of hemostasis was achieved. Methods: Sixty-eight patients with intracerebral hemorrhage were divided into a treatment group (n = 51), and a control group (n = 35). Nimotop solution (10 mg) was administered ...

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Ultra-early hemostatic therapy for intracerebral hemorrhage.

BACKGROUND Intracerebral hemorrhage (ICH) causes higher morbidity and mortality than other forms of stroke and has no proven effective treatment. Hematoma volume is a powerful predictor of outcome after ICH. SUMMARY OF REVIEW Historically, ICH bleeding was considered to be a monophasic event that stopped quickly as a result of clotting and tamponade by surrounding brain tissue. More recently,...

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Hemostatic therapy in experimental intracerebral hemorrhage associated with rivaroxaban.

BACKGROUND AND PURPOSE Rivaroxaban has recently been approved for stroke prevention in atrial fibrillation. However, lack of an effective antidote represents a major concern in the event of intracerebral hemorrhage (ICH). The aims of the present study were to establish a murine model of ICH associated with rivaroxaban, and to examine the effectiveness of different hemostatic factors in preventi...

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Hemostatic activation in spontaneous intracerebral hemorrhage.

BACKGROUND AND PURPOSE There is no in-depth information available on the changes in hemostatic systems in patients in the acute phase of spontaneous intracerebral hemorrhage (ICH). This study was conducted to assess the relationships between the changes in hemostatic systems and clinical parameters in patients in acute-phase ICH. METHODS The records of 358 patients admitted within 6 hours of ...

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Hemostatic therapy should be used for acute treatment of anticoagulation-related intracerebral hemorrhage.

The Questions: (1) Should the patient receive vitamin K and fresh-frozen plasma on evaluation in the emergency department to reverse international normalized ratio? (2) If so, what is the appropriate targeted international normalized ratio level? (3) Should other hemostatic agents such as prothrombin complex concentrates or NovoSeven be used instead of (or in combination with) fresh-frozen plasma?

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ژورنال

عنوان ژورنال: Open Journal of Modern Neurosurgery

سال: 2017

ISSN: 2163-0569,2163-0585

DOI: 10.4236/ojmn.2017.74013